Get A Color Atlas of Comparative Pathology of Pulmonary PDF

By Franz Joel Leong, Veronique Dartois, Thomas Dick

ISBN-10: 1439835276

ISBN-13: 9781439835272

An annual loss of life toll of two million, coupled with emerging drug resistance, highlights the necessity for the improvement of recent medicines, greater diagnostics, and a tuberculosis (TB) vaccine. Addressing those key concerns, a colour Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, scholars, scientists, and medical professionals operating, studying, and educating within the box of TB. It comprises a hundred colour pictures and illustrations that deliver readability to the knowledge provided. The atlas takes the bizarre method of masking a number of species histopathology, arguably the 1st and relatively very likely the one source to take action. It offers an easy, annotated, and visible presentation of the comparative histopathology of TB in human and animal types. The editors have compiled info that is helping TB scientists to differentiate among the positive factors of all significant animal types on hand and to take advantage of them with their strengths and obstacles in brain. The ebook offers assistance for choosing the simplest animal model(s) to reply to particular questions and to check the efficacy of drug applicants.

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Additional info for A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis

Example text

It can grow extracellularly as well as intracellularly, both in culture and inside human lesions. , 1998). Disease Manifestations and Treatment MTB is an obligate human parasite that attacks largely the lungs, although other organ systems can be affected such as the central nervous or the lymphatic system and bones and joints. Classical symptoms of pulmonary TB are chronic cough, fever, night sweats, and weight loss. Infection occurs via inhalation of aerosol droplets. Upon entry into the lungs, the pathogen is taken up by alveolar macrophages where it can multiply, disseminate, and establish foci of infection and lesions in other parts of the lungs.

Tuberculosis (Edinb), 83, 112–115. , and Kaplan, G. 2008. The phenolic glycolipid of Mycobacterium tuberculosis differentially modulates the early host cytokine response but does not in itself confer hypervirulence. Infect Immun, 76, 3027–3036. E. 1977. Animal model of human disease. Pulmonary tuberculosis. Animal model: Experimental airborne tuberculosis in the guinea pig. Am J Pathol, 89, 273–276. V. 2009. Myths and misconceptions: The origin and evolution of Mycobacterium tuberculosis. Nat Rev Microbiol, 7, 537–544.

E. 1977. Animal model of human disease. Pulmonary tuberculosis. Animal model: Experimental airborne tuberculosis in the guinea pig. Am J Pathol, 89, 273–276. V. 2009. Myths and misconceptions: The origin and evolution of Mycobacterium tuberculosis. Nat Rev Microbiol, 7, 537–544. B. 2003. Tuberculosis: A problem with persistence. Nat Rev Microbiol, 1, 97–105. , and Mizuno, S. 2004a. Pathological and immunological profiles of rat tuberculosis. Int J Exp Pathol, 85, 125–134. , and Mizuno, S. 2004b.

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A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis by Franz Joel Leong, Veronique Dartois, Thomas Dick


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