By Edited by Andrew D. Blann Edited by Gregory Y. H. Lip
Urban health center, Birmingham, united kingdom. Discusses the motives and outcomes of blood clots, how antithrombotic treatment works and its makes use of for sufferers. Addresses bleeding hazards, venous thromboembolism, atrial traumatic inflammation, peripheral vascular disorder, center failure, and anticoagulation. ample halftone and colour illustrations. Softcover.
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Extra info for ABC of Antithrombotic
Larger doses have no apparent additional benefit but increase the risk of adverse effects. Aspirin has been shown to reduce the progression of atherosclerosis in a few trials, but this remains unsubstantiated. The role of dipyridamole remains controversial. Several small studies have shown the benefit of giving it in conjunction with aspirin, but it is uncertain if dipyridamole alone is superior to aspirin. In aspirin intolerant patients there is now a clear role for clopidogrel 75 mg once a day.
9 Valvar heart disease and prosthetic heart valves Ira Goldsmith, Alexander G G Turpie, Gregory Y H Lip Thromboembolism and anticoagulant related bleeding are major life threatening complications in patients with valvar heart disease and those with prosthetic heart valves. In these patients effective and safe antithrombotic therapy is indicated to reduce the risks of thromboembolism while keeping bleeding complications to a minimum. Assessment Risk factors that increase the incidence of systemic embolism must be considered when defining the need for starting antithrombotic therapy in patients with cardiac valvar disease and prosthetic heart valves.
Thus, specific antithrombotic therapy is not indicated. However, once again, the presence of peripheral vascular disease needs antiplatelet therapy to reduce all cardiovascular end points. Percutaneous transluminal angioplasty Almost all patients undergoing percutaneous transluminal angioplasty have atherosclerotic peripheral vascular disease. As such, they should all be treated with aspirin or clopidogrel. Studies with radiolabelled platelets have found substantial platelet accumulation at the sites of angioplasty, and antiplatelet treatment reduces this.
ABC of Antithrombotic by Edited by Andrew D. Blann Edited by Gregory Y. H. Lip