New PDF release: An introduction to vascular biology : from basic science to

By Beverley J. Hunt, Lucilla Poston, Michael Schachter, Alison W. Halliday

ISBN-10: 0511063164

ISBN-13: 9780511063169

ISBN-10: 0511119178

ISBN-13: 9780511119170

ISBN-10: 0511545940

ISBN-13: 9780511545948

ISBN-10: 0521796520

ISBN-13: 9780521796521

This up to date and extended re-creation takes complete account of contemporary advancements and conveys the fundamental technological know-how underlying a variety of scientific stipulations together with atherosclerosis, high blood pressure, diabetes, and being pregnant. As with the 1st variation, the book presents an introductory account of vascular biology earlier than prime directly to clarify mechanisms all in favour of ailment methods. The breadth and variety of matters coated during this re-creation do complete justice to this more and more very important sector of medical learn and medication. This multidisciplinary method will swimsuit the wishes of all these looking to refresh their wisdom with the very most modern advances from uncomplicated technology via to scientific perform

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Additional info for An introduction to vascular biology : from basic science to clinical practice

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Bank file 1scm (2). (c) A schematic representation of a myosin molecule. There are two motor domains attached to a coiled -helical rod domain. Each catalytic domain (on the right side) has an ATP site (the circle) and an actin-binding site, which includes a cleft (the v shape). The lever arm is attached flexibly to the catalytic domain and to the rod domain. In muscle, the rod segments aggregate to form the thick filament. Images modified from (d). 5–3 nm show the overall shape of the myosin head and its geometry of attachment to actin.

Requirement of ryanodine receptor subtypes 1 and 2 for Ca(2+)-induced Ca(2+) release in vascular myocytes. J. Biol. , 275, 9596–603. G. & Thorner, J. (1997). RGS proteins and signaling by heterotrimeric G proteins. J. Biol. , 272, 3871–4. 28 A. D. A. et al. (1998). The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science, 280, 69–77. , Goirand, F. & Dumas, M. (1999). Hypoxic pulmonary vasoconstriction. Gen. , 33, 289–97. O. & Godfraind, T. (1994). QuantiWcation of two splicing events in the l-type calcium channel alpha-1 subunit of intestinal smooth muscle and other tissue.

Biochem. , 54, 325–39. D. A. (1997). Molecular determinants of drug binding and action on l-type calcium channels. Annu. Rev. Pharmacol. , 37, 361–96. , Ammendola, A. & Schlossmann, J. (2000). Rising behing NO: cGMP-dependent protein kinases. J. , 113, 1671–6. O. J. (1990). On the passive properties of smooth muscle. In 29 Vascular tone Frontiers in Smooth Muscle Research, ed. Sperelakis, N. , pp. 379–98. New York: Alan R. Liss. , Laporte, R. G. (1996). Mechanisms of smooth muscle contraction. Physiol.

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An introduction to vascular biology : from basic science to clinical practice by Beverley J. Hunt, Lucilla Poston, Michael Schachter, Alison W. Halliday

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