By Kewal K. Jain
Culling jointly excerpts from quite a lot of writings through Dr. Kewal okay. Jain on biotechnology themes as they relate to problems of the apprehensive process, Applications of Biotechnology in Neurology covers a number of functions for these operating in existence sciences and the pharmaceutical sciences, rather these constructing diagnostics and therapeutics for the frightened process. This precise quantity delves into components akin to neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, a variety of tools of bettering systemic management of gear for certain supply to the fearful procedure, together with using nanobiotechnology, biotechnology-based suggestions and items for neuroprotection, in addition to chapters on neurosurgery and customized neurology.
Thorough, state-of-the-art, and thoughtfully geared up, Applications of Biotechnology in Neurology serves as a fantastic consultant, supplemented by way of seventy five tables and sixteen figures in addition to various references from fresh literature in this subject, that are appended to every chapter.
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Extra resources for Applications of Biotechnology in Neurology
In situ hybridization and polymerase chain reaction enable visualization of genes in single cells. The limitation of these techniques is the difﬁculty in analyzing the expression of multiple genes involved in the physiology of an individual cell. Expression proﬁles represent the molecular ﬁngerprints of cells, and differences in the patterns between normal and diseased cells provide information about the molecular pathology at the single cell level. Analysis of messenger RNA (mRNA) levels for various genes in the central nervous system tissues may enhance understanding of the pathophysiology of neurologic disease.
4 Methods of gene transfer as applied to neurologic disorders .... 5 Approaches to controlling gene expression in gene therapy ..... 6 Gene therapy techniques applicable to PD ................................ 7 Transgenic mouse models of human neurogenetic diseases ...... 8 Gene therapy approaches to Duchenne muscular dystrophy ..... 9 Gene therapy strategies for cerebral vasospasm ........................ 10 Neuroprotective gene therapy in animal stroke models ............ 11 Strategies for gene therapy of malignant brain tumors ..............
Jain PharmaBiotech Publications, Basel, 2012a. Kim S, Misra A. SNP Genotyping: Technologies and Biomedical Applications. Annu Rev Biomed Eng 2007;9:289–320. 16 2 Neurogenetics and Neurogenomics Mende S, Storch A, Reichmann H. Gene expression proﬁling of classic mitochondrial disorders. Its value in ﬁnding therapeutic strategies. Nervenarzt 2007;78:1155–9. Wood N (ed) Neurogenetics: A Guide for Clinicians (Paperback). Cambridge University Press, New York, 2012. Chapter 3 Neuroproteomics Introduction The term ‘proteomics’ indicates PROTEins expressed by a genOME and is the systematic analysis of protein proﬁles of tissues.
Applications of Biotechnology in Neurology by Kewal K. Jain