By Giorgia Dalpiaz, Alessandra Cancellieri
This atlas is designed as an easy-to-use reference consultant that identifies and illustrates the main styles of diffuse lung ailments saw on high-resolution computed tomography (HRCT) after which records in additional element the features and appearances of the person ailments, grouped at the foundation in their popular trend. yet another characteristic of the e-book is its interdisciplinary nature: contributions from specialists in a number of specialties are tightly interwoven all through and lots of pathologic correlations are incorporated. much less skilled readers will locate that this atlas, with its wealth of figures and worthwhile colour coding, steers them in the direction of right interpretation whilst faced through the multiplicity and complexity of those illnesses; those who find themselves already specialists, however, will enjoy the special assurance of person ailments, for you to deepen their knowing. on the finish of the ebook, a graphically beautiful and practice-oriented illustrated thesaurus with information and methods bargains one other powerful academic instrument. Given the medical spectrum of illnesses lined, this atlas will turn out priceless for a variety of healthcare staff, particularly radiologists, pulmonologists, and pathologists.
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Extra resources for Atlas of Diffuse Lung Diseases: A Multidisciplinary Approach
41 How to Approach the Diseases Dalpiaz & Cancellieri Septal • Amyloidosis, interstitial • Erdheim–Chester disease (ECD) • Lymphangitic Carcinomatosis (LC) • Pulmonary edema (PE), interstitial • Venoocclusive disease (VOD) Peripheral Some diseases tend to involve the lobule at its periphery. The prototype disease is early usual interstitial pneumonia (UIP), with small scars in a peripheral subpleural (►) and paraseptal distribution. Please also refer to UIP in the chapter “Fibrosing Diseases”. Peripheral • UIP, early • Perilobular opacities (OP) 42 Atlas of Diffuse Lung Diseases Dalpiaz & Cancellieri Pleural/ Subpleural How to Approach the Diseases The image shows a case of pleuroparenchymal fibroelastosis (PPFE), a rare disease consisting in elastotic tissue with a subpleural localization.
Microlitiasis appears as tiny, calcified micronodules filling the alveolar spaces (Figure B). A B LAM Lymphangioleiomyomatosis (LAM) is characterized by the presence of cysts with thin wall containing smooth muscle bundles (Figure A). LAM cells are spindle shaped and plump, with vacuolated cytoplasm. Necrosis Necrosis refers to the premature death of cells in living tissues; this is a detrimental event as opposed to apoptosis, which is actually the programmed cell death. It mostly appears as amorphous material with or without inflammatory cells (Figure B).
Pathology: in BAL fluid, together with pigmented macrophages, a few Langerhans cells, with elongated, cleaved nuclei, are appreciable ( ). 16 Atlas of Diffuse Lung Diseases Bronchoalveolar Lavage (BAL) Dalpiaz & Cancellieri BAL in Lipoid Pneumonia Axial HRCT: basal patchy areas of ground-glass opacities (please also refer to Lipoid Pneumonia in the chapter “Alveolar Diseases”). Pathology: Oil-red positive macrophages. Meyer KC (2012) An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease.
Atlas of Diffuse Lung Diseases: A Multidisciplinary Approach by Giorgia Dalpiaz, Alessandra Cancellieri