By Lori A. Erickson
Atlas of Endocrine Pathology presents a entire compendium of photomicrographs of universal and unusual entities in endocrine pathology. the amount comprises histologic positive factors of standard positive aspects, reactive stipulations, hyperplasia, and tumors. the main invaluable diagnostic gains are illustrated to supply course and clues to the prognosis of endocrine tumors. additionally, photomicrographs spotlight the main pertinent diagnostic beneficial properties in complicated diagnoses in endocrine pathology.
Authored by means of a nationally and the world over famous pathologist, Atlas of Endocrine Pathology is a crucial studying device for these turning into accustomed to the varied entities encountered in endocrine pathology and a priceless reference for training pathologists confronted with demanding diagnoses in endocrine pathology.
Table of Contents
1 Thyroid Histology
3 Graves affliction (Diffuse Hyperplasia)
4 Thyroid Goiter
5 Papillary Thyroid Carcinoma
6 Hyalinizing Trabecular Tumor
7 Follicular Thyroid Neoplasms
8 Hurthle mobile Thyroid Neoplasms
9 Poorly Differentiated Thyroid Carcinoma
10 Anaplastic Thyroid Carcinoma
11 Tumors of C Cells
12 strange Thyroid Tumors
13 Metastases to Thyroid
14 Parathyroid Histology
15 Parathyroid Hyperplasia
16 Parathyroid Adenoma
17 Parathyroid Carcinoma
19 Metastases to Parathyroid
20 Adrenal Gland Histology
21 Adrenal Cysts
22 Adrenal Cortical Hyperplasia
23 Adrenal Cortical Adenoma
24 Adrenal Cortical Carcinoma
25 Adrenal Myelolipoma
26 Pheochromocytoma and Adrenal Medullary Hyperplasia
27 Ganglioneuroma and Neuroblastoma
28 strange Adrenal Tumors
29 Metastases to the Adrenal Gland
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Additional resources for Atlas of Endocrine Pathology (Atlas of Anatomic Pathology)
This thyroid has multiple ill-defined firm masses of PTC with a granular white cut surface. Tumors may be single or multifocal and bilateral. The mean tumor size is 2–3 cm, although size may vary greatly Fig. 2 Classic papillary thyroid carcinoma. Invasive PTC is shown with a lymphocytic infiltrate at the periphery. The stroma in PTC often is abundant, fibrous, and sclerotic Fig. 3 Classic papillary thyroid carcinoma. Prominent papillae with fibrovascular cores lined by epithelial cells with characteristic cytologic features are seen in this PTC.
1990;336(8717):754. 3. Brandle M, et al. Medullary thyroid carcinoma in Graves’ disease. Clin Endocrinol. 1999;50(4):545–6. 4. Chao TC, Lin JD, Chen MF. Surgical treatment of thyroid cancers with concurrent Graves disease. Ann Surg Oncol. 2004;11(4): 407–12. 5. Pascual Corrales E, et al. Incidental differentiated thyroid carcinoma is less prevalent in Graves’ disease than in multinodular goiter. Endocrinol Nutr. 2012;59(3):169–73. 6. Erickson LA, et al. p27kip1 expression distinguishes papillary hyperplasia in Graves’ disease from papillary thyroid carcinoma.
This growth pattern is more common in younger patients, often multicentric, and associated with extrathyroid extension, nodal metastases, and vascular invasion [34, 35]. Encapsulated FVPTCs have less intratumor fibrosis (18 %), extrathyroid extension (5 %), positive margins (2 %), and lymph node metastases (5 %) than nonencapsulated FVPTCs with diffuse/infiltrative growth (88, 65 , 50, and 65 %, respectively) . Encapsulated tumors with vascular or capsular invasion may be more aggressive than those without invasion [26, 27].
Atlas of Endocrine Pathology (Atlas of Anatomic Pathology) by Lori A. Erickson