By Pei Hui, Natalia Buza (auth.)
This atlas is devoted particularly to gynecologic frozen part analysis and addresses specialist perform gaps resembling excessive diagnostic mistakes expense, sluggish turnaround time, and inefficient conversation among surgeons and pathologists on the time of intraoperative frozen part session of gynecologic specimens. The layout of the quantity is a mixture of concise textual content and top of the range gross and frozen part microscopic photographs, meticulously chosen from the wonderful number of pathology specimens of gynecologic tumors supplied at Yale-New Haven medical institution some time past a long time. common entities with diagnostic pitfalls are balanced with much less universal lesions. options to acknowledge their diagnostic gains are emphasised, as well as the influence on optimum surgical procedure of sufferers with gynecologic melanoma. the indicators, barriers, morphologic diagnostic standards and pitfalls of frozen part session in gynecologic pathology are completely reviewed with an final target of heading off sufferer mismanagement in real-time. prime quality frozen part microscopic illustrations relief the popularity of morphologic styles and function quickly reference in the course of intraoperative session.
Written by means of specialists within the box, Atlas of Intraoperative Frozen part analysis in Gynecologic Pathology is a useful source for pathologists in any respect career/expertise degrees who're curious about intraoperative session of their day-by-day medical perform.
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Extra info for Atlas of Intraoperative Frozen Section Diagnosis in Gynecologic Pathology
Differential diagnosis – Endocervical glandular hyperplasia of either lobular or diffuse type 3 Uterine Cervix – – – – – Endocervicosis Tunnel clusters Mesonephric hyperplasia Mesonephric adenocarcinoma Cervical involvement by mucinous endometrial adenocarcinoma • Diagnostic pitfalls/key intraoperative consultation issues – Separation from various nonneoplastic conditions is based on their superficial mucosal location, wellcircumscribed border, and lack of infiltrative growth, significant cytological atypia, mitotic activity, and stromal response.
Absence of significant cytological atypia and mitotic activity and presence of tubal-type ciliated cells are helpful features separating tubo-endometrioid metaplasia from cervical adenocarcinoma in situ Tumorlike Conditions of the Cervix Squamous Metaplasia • Very common condition involving the cervical transformation zone or an endocervical polyp. • Squamous metaplasia may be extensive, frequently involving endocervical glands, simulating squamous intraepithelial lesion or even invasive squamous cell carcinoma (Fig.
Hui, N. 1007/978-3-319-21807-6_3 27 28 3 Uterine Cervix Tumorlike Conditions of the Cervix Tunnel Clusters Endocervical Polyp • Localized proliferation of endocervical glands, commonly seen in multigravida women. • Type A tunnel cluster is noncystic, consisting of crowded endocervical glands with round borders. Irregular glands with mild atypia may be seen, but mitotic activity is generally absent. • Type B tunnel cluster consists of round clusters of packed glands with cystic dilatation that are covered by flattened epithelial cells.
Atlas of Intraoperative Frozen Section Diagnosis in Gynecologic Pathology by Pei Hui, Natalia Buza (auth.)